IGKC Mouse Monoclonal Antibody [Clone ID: KLC709]
Other products for "IGKV1D-16"
Specifications
Product Data | |
Clone Name | KLC709 |
Applications | FC, IHC |
Recommended Dilution | ELISA: Use Antibody without BSA for Coating. Flow Cytometry: 0.5-1 μg/106 cells. Immunohistochemistry on Frozen Sections: 0.5-1 μg/ml for 30 min at RT. Positive Control: 293T, Raji or hPBL cells, Tonsil or Spleen. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Recombinant human Ig kappa chain. |
Specificity | This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant. Cellular Localization: Cell Surface, cytoplasmic and secreted. |
Formulation | 10mM PBS State: Purified State: Liquid purified IgG fraction from Bioreactor Concentrate Stabilizer: 0.05% BSA Preservative: 0.05% Sodium Azide |
Concentration | lot specific |
Purification | Protein A/G Chromatography |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C. |
Stability | Shelf life: one year from despatch. |
Predicted Protein Size | ~22.5 kDa |
Gene Name | immunoglobulin kappa constant |
Database Link | |
Synonyms | HCAK1, Ig Kappa Chain C Region, IGKC, Immunoglobulin KM |
Reference Data |
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