CKMT1B Mouse Monoclonal Antibody [Clone ID: AT17A2]

CAT#: AM50081PU-S

CKMT1B mouse monoclonal antibody, clone AT17A2, Purified

Product Images

The cell lysates of HeLa (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human CKMT1A antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Specifications

Product Data

• Clone Name: AT17A2
• Applications: ELISA, FC, IF, WB
• Recommended Dilution: ELISA.
  Western blot.
  Flow Cytometry.
  Immunofluorescence.
  Recommended starting dilution is 1:1000.
  
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Recombinant human CKMT1A (40-417aa) purified from E. coli
• Formulation: PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein-A affinity chromatography
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: creatine kinase, mitochondrial 1B
• Database Link:
  Entrez Gene 548596 HumanEntrez Gene 1159 Human
  UniProt ID P12532
• Background: CKMT1A, also known as Creatine kinase, mitochondrial 1A, is 417 amino acid protein. Mitochondrial creatine kinase (MtCK) exists as two isoenzymes, sarcomeric MtCK (CKMT2) and ubiquitous MtCK (CKMT1). It is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis.
• Synonyms: CKMT1A, CKMT1B, U-MtCK, Mia-CK, Creatine kinase U

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Arginine and proline metabolism, Metabolic pathways