LSM2 Mouse Monoclonal Antibody [Clone ID: AT2B2]

CAT#: AM50011PU-N

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LSM2 mouse monoclonal antibody, clone AT2B2, Purified


Product Datasheet for 'AM50011PU-N'


USD 340.00


Availability*
2 Weeks

Size
    • 100 ul


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Specifications

Product Data
Clone Name 1G7
Applications ELISA, WB
Recommended Dilution The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1,000~1:3,000.
Reactivity Human
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Recombinant human LSm2 (1-95aa) purified from E. coli
Formulation PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol
State: Purified
State: Liquid purified Ig fraction
Concentration 1.0 mg/ml
Purification Protein-G affinity chromatography
Background LSM2 is a member of the LSm family of RNA-binding proteins. Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner. Component of the cytoplasmic complex which is thought to be involved in mRNA degradation by activating the decapping step. Component of the nuclear LSM2 complex, which is involved in splicing of nuclear mRNAs. LSM2 associates with multiple snRNP complexes containing the U6 snRNA It binds directly to the U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes. It probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping. LSM2 binds specifically to the 3'-terminal U-tract of U6 snRNA. LSM2-LSM8 probably is involved in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA.
Synonyms C6orf28, G7B
Reference Data
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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