Prostate Specific Antigen (KLK3) Mouse Monoclonal Antibody [Clone ID: C3F12]

CAT#: AM32796PU-N

Prostate Specific Antigen (KLK3) mouse monoclonal antibody, clone C3F12, Purified

Product Images

Immunohistochemistry on Paraffin Section of Human prostate using PSA Antibody

• 

  Formalin-Fixed, Paraffin-Embedded Human Prostate tissue stained with PSA Antibody at 10 ug/ml after heat-induced antigen retrieval.

Specifications

Product Data

• Clone Name: C3F12
• Applications: Elispot, FC, IF, IHC, WB
• Recommended Dilution: ELISPOT.
  Western blot.
  Flow Cytometry.
  Immunocytochemistry.
  Immunohistochemistry on Frozen Sections.
  Immunohistochemistry on Paraffin Sections (10 μg/ml).
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: PSA/Prostate Specific Antigen antibody was raised against prostate specific antigen (PSA)
• Specificity: Recognizes Human PSA.
  Other species not tested.
• Formulation: 50mM Phosphate buffer pH 7.4, 0.1mM NaCl
  State: Purified
  State: Liquid purified IgG fraction
  Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Purification: Protein A Chromatography
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: kallikrein related peptidase 3
• Database Link:
  Entrez Gene 354 Human
  UniProt ID P07288
• Background: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma.
  Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a 33 kDa glycoprotein encoded in humans by the KLK3 gene. PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland.
  PSA is present in small quantities in the serum of men with healthy prostates, but is often elevated in the presence of prostate cancer or other prostate disorders.
• Synonyms: Prostate-specific antigen, Semenogelase, Gamma-seminoprotein, P-30 antigen