Cd4 Rat Monoclonal Antibody [Clone ID: GK1.5]
Cd4 rat monoclonal antibody, clone GK1.5, FITC, Purified
|Recommended Dilution||Flow Cytometry (Cell Surface): 0.031-1.0 μg/106 cells.|
|Specificity||Recognizes Mouse CD4. Other species not tested.|
|Formulation||PBS, pH 7.4
State: Liquid purified IgG fraction
Preservative: 0.05% Sodium Azide
|Purification||Protein G Chromatography|
|Storage||Store undiluted at 2-8°C.
DO NOT FREEZE!
This product is photosensitive and should be protected from light.
|Stability||Shelf life: one year from despatch.|
|Predicted Protein Size||52 kDa|
CD4 (cluster of differentiation 4) is a glycoprotein expressed on the surface of T helper cells, regulatory T cells, monocytes, macrophages, and dendritic cells. It is a member of the immunoglobulin superfamily. On T cells, it is the co-receptor for the T cell receptor (TCR) and amplifies the signal generated by the TCR by recruiting the tyrosine kinase lck that is essential for activating many molecules involved in the signaling cascade of an activated T cell. It is an important component of the immune system and is also the cellular receptor for HIV-1. It consists of a cytoplasmic tail, one transmembrane region, and four extracellular domains, D1-D4.
|Synonyms||T-cell surface antigen T4/Leu-3|