Cd4 Rat Monoclonal Antibody [Clone ID: GK1.5]

CAT#: AM32703AF-N

Rat monoclonal anti-CD4 antibody, cloneGK1.5, Azide Free

 Product Datasheet for 'AM32703AF-N'

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USD 210.00

In Stock

    • 0.1 mg

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Product Data
Clone Name GK1.5
Applications FC
Recommend Dilution ICC/IF, IHC, FC, IP
Reactivity Mouse
Host Rat
Clonality Monoclonal
Isotype IgG2b
Formulation PBS, pH 7.4
Concentration 0.5 mg/ml
Purification Protein G Chromatography
Predicted Protein Size ~51.7kDa
Gene Name CD4 antigen
Background CD4 (cluster of differentiation 4) is a glycoprotein expressed on the surface of T helper cells, regulatory T cells, monocytes, macrophages, and dendritic cells. It is a member of the immunoglobulin superfamily. On T cells, it is the co-receptor for the T cell receptor (TCR) and amplifies the signal generated by the TCR by recruiting the tyrosine kinase lck that is essential for activating many molecules involved in the signaling cascade of an activated T cell. It is an important component of the immune system and is also the cellular receptor for HIV-1. It consists of a cytoplasmic tail, one transmembrane region, and four extracellular domains, D1-D4.
Synonyms L3T4|Ly-4
Reference Data

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