Staphylococcus epidermidis Mouse Monoclonal Antibody [Clone ID: 17-5]
Staphylococcus epidermidis mouse monoclonal antibody, clone 17-5, Supernatant
|Recommended Dilution||ELISA (1/10).
Agglutination: Prepare bacteria suspension in a physiological salt solution and place 10 microl on glass slide. Add 10 microl antibody solution, mix well and watch clumping.
|Specificity||The antibody reacts with several Staphylococcus strains using ELISA.
It does not react with several members of the Enterobacteriaceae
State: Liquid Supernatant in RPMI
Preservative: 0.02% Sodium Azide
|Concentration||> 0.2 mg/ml|
Store the antibody undiluted at 2-8°C
|Stability||Shelf life: one year from despatch.|
|Background||Staph. epidermidis is normally resident in the skin flora, the gut and upper respiratory tract. It is a true opportunistic pathogen, requiring a major breach in the host's infection to establish infection, and invariably is hospital acquired. It is associated with skin penetration by implanted prostheses, for example Spitz Holter valves used to treat hydrocephalus, prosthetic heart valves, IV lines, intraperitoneal catheters and orthopaedic prostheses. It is a major cause of bacteraemia in neutropenics and in all infections there is a risk of endocarditis. It is also a serious neonatal infection, particularly in very low birth weight infants. Staph. epidermidis produces some toxins but their significance is unknown. Adherence to a foreign surface is facilitated by the production of a viscous extracellular (proteoglycans) slime. Staph. epidermidis is coagulase negative.|