Apolipoprotein B (APOB) Mouse Monoclonal Antibody [Clone ID: 12G10]

CAT#: AM32212PU-N

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Mouse monoclonal anti-Apolipoprotein B / Apo B antibody, clone12G10, Purified


 Product Datasheet for 'AM32212PU-N'

USD 370.00


Availability*
2 Weeks

Size
    • 1 ml


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Specifications

Product Data
Clone Name 12G10
Applications C, E
Recommend Dilution IHC, ElISA
Reactivity Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Concentration 0,5 mg/ml (after reconstitution)
Purification Sodium sulfate + DEAE-cellulose, gradient elution
Predicted Protein Size ~512.7 kDa
Gene Name apolipoprotein B
Background This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq, Jul 2008]
Synonyms apoB-48; apoB-100; FLDB; LDLCQ4
Reference Data
Protein Families Druggable Genome, Transmembrane
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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ANTIBODY VALIDATION 101
BOGO Free lysates
68 Mouse Clones