Tumor necrosis factor (TNF-alpha) Rat Monoclonal Antibody [Clone ID: V1q]

CAT#: AM32022PU-N

Tumor necrosis factor (TNF-alpha) rat monoclonal antibody, clone V1q, Purified

Specifications

Product Data

• Clone Name: V1q
• Applications: FN
• Recommended Dilution: Flow Cytometry: Use 1/10 as typical starting working dilution.
  Neutralization of Biological Activity: Dilutions have to be made according to the amounts TNF-alpha to be inactivated.
• Reactivities: Mouse
• Host: Rat
• Isotype: IgD
• Clonality: Monoclonal
• Specificity: This antibody reacts with both natural and recombinant TNF-alpha and shows Neutralizing Activity.
• Formulation: PBS
  State: Purified
  State: Liquid (0.2 μm filtered) purified IgG fraction
  Stabilizer: 0.1% BSA
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C.
  
• Stability: Shelf life: one year from despatch.
• Gene Name: tumor necrosis factor
• Database Link:
  Entrez Gene 21926 Mouse
  UniProt ID P06804
• Background:

  Tumor Necrosis Factor alpha (TNF-alpha) is a cytokine which has various immunomodulatory, antitumor and toxic effects. TNF-alpha has been detected in various inflammatory status and appears to be a critical mediator in the lethality of septic shock. Furthermore, TNF-alpha has also been found in inflammatory foci such as synovial effusions in rheumatoid arthritis, systemic circulation in septic shock, parasitemia and rejection of renal transplants.

• Synonyms: TNF, TNF-a, TNFA, TNFSF2, Cachectin