PIP5K2 alpha (PIP4K2A) (304-366) Mouse Monoclonal Antibody [Clone ID: 3A3]

CAT#: AM31818PU-N

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PIP5K2 alpha (PIP4K2A) (304-366) mouse monoclonal antibody, clone 3A3, Purified

 Product Datasheet for 'AM31818PU-N'

USD 475.00

2 Weeks

    • 50 ug

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Product Data
Clone Name 3A3
Applications ELISA, IHC, WB
Recommend Dilution ELISA.
Immunohistochemistry on Paraffin Sections: 5 µg/ml.
Western Blot: 1/500 - 1/1000.
Reactivity Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen PIP4K2A antibody was raised against pIP5K2A (NP_005019, 304 a.a. ~ 366 a.a) partial recombinant protein with GST tag.
Specificity This antibody reacts to PIP4K2A / PIP5K2A at aa 304-366.
Formulation PBS, pH 7.4
State: Purified
State: Liquid purified Ig fraction
Concentration 0.48 mg/ml
Purification Affinity chromatography on Protein A
Gene Name Homo sapiens phosphatidylinositol-5-phosphate 4-kinase, type II, alpha (PIP4K2A)
Background Catalyzes the phosphorylation of phosphatidylinositol 5-phosphate (PtdIns5P) on the fourth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May exert its function by regulating the levels of PtdIns5P, which functions in the cytosol by increasing AKT activity and in the nucleus signals through ING2. May regulate the pool of cytosolic PtdIns5P in response to the activation of tyrosine phosphorylation.
Synonyms PIP4KII-alpha, PIP5K2, PIP5KIII, Diphosphoinositide kinase 2-alpha, PtdIns(4)P-5-kinase B isoform, PtdIns(4)P-5-kinase C isoform, PtdIns(5)P-4-kinase isoform 2-alpha
Reference Data
Protein Families Druggable Genome
Protein Pathways Inositol phosphate metabolism, Phosphatidylinositol signaling system, Regulation of actin cytoskeleton
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