PIM1 Mouse Monoclonal Antibody [Clone ID: 6A2]
PIM1 mouse monoclonal antibody, clone 6A2, Purified
Product Datasheet for 'AM31122PU-N'
|Applications||ELISA, IF, IHC|
Immunofluorescence: 10 µg/ml.
Immunohistochemistry on Paraffin Sections: 5 µg/ml.
|Immunogen||PIM1 antibody was raised against recombinant protein|
|Specificity||This antibody reacts to PIM1.|
|Formulation||PBS, pH 7.2
State: Liquid purified Ig fraction
|Purification||Affinity chromatography on Protein A|
|Gene Name||Homo sapiens Pim-1 proto-oncogene, serine/threonine kinase (PIM1), transcript variant 1|
|Background||PIM-1, an immediate early gene in the PIM subfamily of kinases, has been implicated in the regulation of proliferation, differentiation and cell survival of lymphoid and myeloid cells. PIM-1 is a cytoplasmic modulator of the interleukin-3 signal transduction pathway. Two isoforms of PIM-1 exist: the larger protein is an amino-terminal extension of the smaller protein and is synthesized by alternative translation initiation at an upstream CUG codon.|
|Protein Families||Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase|
|Protein Pathways||Acute myeloid leukemia, Jak-STAT signaling pathway|
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