Siglec 7 (SIGLEC7) Mouse Monoclonal Antibody [Clone ID: 6-434]
Siglec 7 (SIGLEC7) mouse monoclonal antibody, clone 6-434, PE
|Recommended Dilution||Flow Cytometry analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.|
|Immunogen||Human dendritic cells|
|Specificity||This antibody recognizes CD328 (Siglec-7), a 75 kDa transmembrane glycoprotein expressed mainly on NK cells, dendritic cells and monocytes.|
|Formulation||Phosphate buffered saline (PBS)
State: Liquid purified Ig fraction
Stabilizer: 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA)
Preservative: 15 mM sodium azide
|Storage||Store the antibody undiluted at 2-8°C.
DO NOT FREEZE!
This product is photosensitive and should be protected from light.
|Stability||Shelf life: one year from despatch.|
|Background||CD328, also known as Siglec-7 or p75/AIRM1, is a 75 kDa type I transmembrane glycoprotein of sialic acid-binding immunoglobulin-like lectin (Siglec) family. CD328 binds to sialylated glycans with alpha2,6 sialyl and alpha2,8 disyalyl residues and mediates sialic acid-dependent cell-cell binding. As it contains in its intracellular part the immunoreceptor tyrosine-based inhibitory motif (ITIM), it serves as an inhibitory receptor, e.g. of NK cells.|
|Synonyms||Siglec-7, QA79 membrane protein, p75, D-siglec, CDw328, AIRM1|