Siglec 7 (SIGLEC7) Mouse Monoclonal Antibody [Clone ID: 6-434]

CAT#: AM26779PU-N

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Siglec 7 (SIGLEC7) mouse monoclonal antibody, clone 6-434, Purified


Product Datasheet for 'AM26779PU-N'


USD 220.00


Availability*
2 Weeks

Size
    • 100 ug


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Specifications

Product Data
Clone Name 6-434
Applications FC
Recommended Dilution Flow cytometry.
Reactivity Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human dendritic cells
Specificity This antibody recognizes CD328 (Siglec-7), a 75 kDa transmembrane glycoprotein expressed mainly on NK cells, dendritic cells and monocytes.
Formulation Phosphate buffered saline (PBS)
State: Purified
State: Liquid Ig fraction
Preservative: 15 mM sodium azide, approx. pH 7.4
Concentration 1.0 mg/ml
Purification Protein-A affinity chromatography (> 95% pure by SDS-PAGE)
Storage Store undiluted at 2-8°C.
DO NOT FREEZE!
Stability Shelf life: one year from despatch.
Background CD328, also known as Siglec-7 or p75/AIRM1, is a 75 kDa type I transmembrane glycoprotein of sialic acid-binding immunoglobulin-like lectin (Siglec) family. CD328 binds to sialylated glycans with alpha2,6 sialyl and alpha2,8 disyalyl residues and mediates sialic acid-dependent cell-cell binding. As it contains in its intracellular part the immunoreceptor tyrosine-based inhibitory motif (ITIM), it serves as an inhibitory receptor, e.g. of NK cells.
Synonyms Siglec-7, QA79 membrane protein, p75, D-siglec, CDw328, AIRM1
Reference Data
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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