DC SIGN (CD209) Mouse Monoclonal Antibody [Clone ID: UW60.1]

CAT#: AM26379AC-N

DC SIGN (CD209) mouse monoclonal antibody, clone UW60.1, APC

Conjugation: Unconjugated APC


USD 362.00

2 Weeks*

Size
    • 100 Tests

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Specifications

Product Data
Clone Name UW60.1
Applications FC
Recommended Dilution Flow cytometry analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension.
Reactivities Human
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen CD209-His-tagged fusion protein
Specificity This antibody recognizes human CD209 (DC-SIGN), a 44 kDa transmembrane receptor expressed on the surface of dendritic cells and macrophages.
Formulation Phosphate buffered saline (PBS)
Label: APC
State: Liquid Ig fraction
Stabilizer: 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA)
Preservative: 15 mM sodium azide
Label: Conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use.
Conjugation APC
Storage Store the antibody at 2-8°C.
DO NOT FREEZE!
This product is photosensitive and should be protected from light.
Stability Shelf life: one year from despatch.
Gene Name CD209 molecule
Background CD209, also known as DC-SIGN (dendritic cell-specific ICAM-3-grabbing nonintegrin) is a transmembrane receptor expressed on the surface of dendritic cells and macrophages, which recognizes numerous pathogens ranging from parasites to viruses. Its N-terminal domain is transmembrane, whereas a tandem-repeat neck domain and the C terminal C-type lectin carbohydrate recognition domain have dual function as a pathogen recognition receptor and a cell adhesion receptor. The neck region is responsible for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. A ligand of CD209 is also CD50 (ICAM-3).
Synonyms DCSIGN1, DCSIGN, DC-SIGN1, CLEC4L, Dendritic Cell Marker
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.