liver FABP (FABP1) Mouse Monoclonal Antibody [Clone ID: L2B10]

CAT#: AM26273BT-N

liver FABP (FABP1) mouse monoclonal antibody, clone L2B10, Biotin

Specifications

Product Data

• Clone Name: L2B10
• Applications: ELISA, IHC, WB
• Recommended Dilution: Immunohistochemistry on fozen sections: The typical starting working dilution is 1:50.
  Immunoassay.
  Western blot: The typical starting working dilution is 1:50.
• Reactivities: Baboon, Canine, Human, Porcine, Rat
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Specificity:
  The monoclonal antibody L2B10 recognizes human liver fatty acid binding protein (L-FABP) of both natural and recombinant origin.
  Furthermore, the antibody can be used for the purification of human L-FABP.
  Weak reactivity with Human H-FABP.
• Formulation: PBS
  Label: Biotin
  State: Liquid 0.2 µm filtered Ig fraction
  Stabilizer: 0.1% bovine serum albumin
  Preservative: 0.02% sodium azide
• Concentration: lot specific
• Purification: Protein G
• Conjugation: Biotin
• Storage:

  Store at 2 - 8 °C.
  

• Stability: Shelf life: one year from despatch.

• Gene Name: fatty acid binding protein 1
• Database Link:
  Entrez Gene 2168 Human
  UniProt ID P07148
• Background: The L-FABP protein is derived from the human FABP1 gene. FABPs are small intracellular proteins (~13-14 kDa) with a high degree of tissue specificity that bind long chain fatty acids. They are abundantly present in various cell types and play an important role in the intracellular utilization of fatty acids, transport and metabolism. There are at least nine distinct types of FABP, each showing a specific pattern of tissue expression. Due to its small size, FABP leaks rapidly out of ischemically damaged necrotic cells leading to a rise in serum levels. Ischemically damaged tissues are characterized histologically by absence (or low presence) of FABP facilitating recognition of such areas. L-FABP is localized in the liver, kidney and intestinal epithelium.
• Synonyms: FABPL, L-FABP, Liver-type fatty acid-binding protein