CD61 (ITGB3) Mouse Monoclonal Antibody [Clone ID: VIPL2]

CAT#: AM26143PU-N

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CD61 (ITGB3) mouse monoclonal antibody, clone VIPL2, Aff - Purified


Product Datasheet for 'AM26143PU-N'


 Cited in 6 publications.

USD 220.00


Availability*
2 Weeks

Size
    • 100 ug


Product images

Specifications

Product Data
Clone Name VIPL2
Applications FC, IHC, WB
Recommended Dilution Flow Cytometry
Western blot.
Immunohistochemistry on Frozen Sections.
Reactivity Human, Primate
Host Mouse
Isotype IgG1
Clonality Monoclonal
Specificity This Mouse monoclonal antibody VIPL2 recognizes CD61, a 90-110 kDa transmembrane glycoprotein of integrin family, expressed on platelets, megacaryocytes, osteoclasts, endothelial cells and other cell types, including leucocytes and smooth muscle cells. HLDA V.; WS Code 5T-124
Formulation Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
State: Aff - Purified
State: Liquid Ig fraction
Concentration 1.0 mg/ml
Purification Protein-A affinity chromatography (> 95% pure by SDS-PAGE)
Storage Store undiluted at 2-8°C.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens integrin subunit beta 3 (ITGB3)
Background CD61 (beta3 integrin) is a transmembrane glycoprotein, which associates with CD41 or CD51 molecules to form heterodimeric adhesion receptores. CD41/CD61 complex is one of the earliest markers of the megakaryocytic lineage. It binds to fibronectin, fibrinogen and von Willebrand factor, and is involved in platelet aggregation. CD51/CD61 complex has similar binding properties and is involved in modulating migration and survival of angiogenic endothelial cells.
Synonyms Integrin beta-3, GP3A, GPIIIa
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Hypertrophic cardiomyopathy (HCM), Regulation of actin cytoskeleton

Citations (6)

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