Laminin alpha 4 (LAMA4) Mouse Monoclonal Antibody [Clone ID: 3H2]
Product Data | |
Clone Name | 3H2 |
---|---|
Application | ELISA, IHC, IP, WB |
Recommended Dilution | ELISA: 1:64 000. Western blot (reduced conditions): 1:1 000 - 1:2 000. Immunoprecipitation: 1:20. Immunohistochemistry on frozen sections: 1:100 - 1:200. |
Reactivity | Human |
Antibody Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Immunoaffinity-purified Laminin 411 (laminin-8 (alpha4beta1gamma1) from platelets |
Specificity | This antibody detects Laminin alpha 4. |
Buffer | PBS pH 7.4, with 0.09% sodium azide State: Purified State: Liquid Ig fraction |
Concentration | lot specific |
Purification | Ion exchange chromatography |
Conjugation | Unconjugated |
Storage | Upon receipt, store (in aliquots) at -20 to -70 °C. Avoid repeated freezing and thawing. |
Stability | Shelf life: One year from despatch. |
Shipping | Blue Ice |
Gene Name | laminin subunit alpha 4 |
Database Link | |
Background | Laminins are a family of large heterotrimeric proteins that promote cell adhesion and migration via integrins and other cell-surface receptors. They are major components of basement membranes of blood vessels and other tissue compartments, and are synthesized by numerous cell types. Through combination,laminin chains constitute 15 laminin isoforms. Laminin isoforms, particularly their alpha chain, are expressed in a celland tissue-specific manner, and are differentially recognized by integrins. |
Synonyms | LAMA4, Laminin subunit alpha-4 |
Reference Data | |
Protein Families | Druggable Genome, Secreted Protein |
Protein Pathways | ECM-receptor interaction, Focal adhesion, Pathways in cancer, Small cell lung cancer |
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