Myocilin (MYOC) Mouse Monoclonal Antibody [Clone ID: 4F8]
Mouse monoclonal anti-Myocilin antibody, clone4F8
Product Datasheet for 'AM20919PU-N'
|Applications||ELISA, IHC, WB|
|Recommend Dilution||ElISA, IHC, WB|
|Immunogen||MYOC / Myocilin antibody was raised against mYOC (AAH29261, 36 a.a. ~ 135 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Formulation||PBS, pH 7.4|
|Purification||Protein A Chromatography|
|Predicted Protein Size||~56.8 kDa|
|Background||MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.|
|Synonyms||GLC1A; GPOA; JOAG; JOAG1; TIGR|
|Protein Families||Druggable Genome, Secreted Protein|
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