ABCA1 (1800-2260) Mouse Monoclonal Antibody [Clone ID: AB1.G6]

CAT#: AM20835PU-N

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ABCA1 (1800-2260) mouse monoclonal antibody, clone AB1.G6, Aff - Purified


 Product Datasheet for 'AM20835PU-N'

USD 370.00


Availability*
2 Weeks

Size
    • 100 ug


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Specifications

Product Data
Clone Name AB1.G6
Applications ELISA, IHC, IP, WB
Recommend Dilution ELISA: 3-6 µg/ml.
Western Blot: 1/1000–1/2000.
Immunoprecipitation.
Immunohistochemistry on Paraffin Sections.
Reactivity Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Peptides amino acids 1800-2260
Specificity This antibody recognizes ABCA1 (1800-2260).
Formulation PBS, pH 7.4 with 0.05% Sodium Azide as preservative
State: Aff - Purified
State: Liquid purified Ig fraction
Concentration 1.0 mg/ml
Gene Name Homo sapiens ATP binding cassette subfamily A member 1 (ABCA1)
Background Mutations in the ABCA1 gene (ATP-binding cassette transporter 1) are associated with Tangier disease (TD). TD is an autosomal recessive disorder results from an absence of plasma HDL, cholesterol ester depositing in the reticulo-endothelial system and disorders in cellular lipid trafficking. It is expressed on the plasma membrane and the Golgi complex, and is regulated by cholesterol flux. Regulation of the cholesterol flux between HDL and macrophages is competitive between ABCA1 and SR-BI.
Synonyms ABC1, ABC-1, CERP
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways ABC transporters
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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