ABCA1 (1800-2260) Mouse Monoclonal Antibody [Clone ID: AB1.G6]
ABCA1 (1800-2260) mouse monoclonal antibody, clone AB1.G6, Aff - Purified
Product Datasheet for 'AM20835PU-N'
|Applications||ELISA, IHC, IP, WB|
|Recommend Dilution||ELISA: 3-6 µg/ml.
Western Blot: 1/1000–1/2000.
Immunohistochemistry on Paraffin Sections.
|Immunogen||Peptides amino acids 1800-2260|
|Specificity||This antibody recognizes ABCA1 (1800-2260).|
|Formulation||PBS, pH 7.4 with 0.05% Sodium Azide as preservative
State: Aff - Purified
State: Liquid purified Ig fraction
|Gene Name||Homo sapiens ATP binding cassette subfamily A member 1 (ABCA1)|
|Background||Mutations in the ABCA1 gene (ATP-binding cassette transporter 1) are associated with Tangier disease (TD). TD is an autosomal recessive disorder results from an absence of plasma HDL, cholesterol ester depositing in the reticulo-endothelial system and disorders in cellular lipid trafficking. It is expressed on the plasma membrane and the Golgi complex, and is regulated by cholesterol flux. Regulation of the cholesterol flux between HDL and macrophages is competitive between ABCA1 and SR-BI.|
|Synonyms||ABC1, ABC-1, CERP|
|Protein Families||Druggable Genome, Transmembrane|
|Protein Pathways||ABC transporters|
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.