Tryptophan Hydroxylase (TPH1) Mouse Monoclonal Antibody [Clone ID: Try-63]

CAT#: AM20674PU-N

Tryptophan Hydroxylase (TPH1) mouse monoclonal antibody, clone Try-63, Purified

Specifications

Product Data

• Clone Name: Try-63
• Applications: WB
• Recommended Dilution: Western Blot: 0.5 - 1 μg/ml.
• Reactivities: Human, Rabbit, Rat
• Host: Mouse
• Isotype: IgG3
• Clonality: Monoclonal
• Immunogen: Recombinant rabbit tryptophan hydroxylase
• Specificity: This antibody reacts to Tryptophan 5-hydroxylase 1.
• Formulation: 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative
  State: Purified
  State: Lyphilized purified Ig fraction
• Reconstitution Method: Restore with 1.2% sodium acetate or neutral PBS
• Concentration: 0,1 mg/ml (after reconstitution with PBS)
• Purification: Affinity chromatography
• Conjugation: Unconjugated
• Storage: Prior to reconstitution store at -20°C.
  Following reconstitution store undiluted at 2-8°C for one month
  or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: tryptophan hydroxylase 1
• Database Link:
  Entrez Gene 24848 RatEntrez Gene 7166 Human
  UniProt ID P17752
• Background: Tryptophan hydroxylase is the rate-limiting enzyme in the synthesis of serotonin (5-hydroxytryptamine,or 5HT). Tryptophan hydroxylaseatalyzes the iopterin-dependent monooxygenation of tryptophan to5-hydroxytryptophan (5HT), which is subsequently decarboxylated to form the neurotransmitter serotonin. Human tryptophan hydroxylase (TPH) is mapped to chromosome 11p15.3-p14 by in situhybridization.
• Synonyms: Tryptophan 5-monooxygenase 1, TPRH, TRPH

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Tryptophan metabolism