Nebulin (NEB) Mouse Monoclonal Antibody [Clone ID: Neb-20]
Product Data | |
Clone Name | Neb-20 |
---|---|
Application | WB |
Recommended Dilution | Western Blot: 1 - 2 μg/ml. |
Reactivity | Chicken, Frog, Human, Mouse, Rat |
Antibody Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Chicken breast nebulin |
Specificity | This antibody reacts to Nebulin. |
Buffer | 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative State: Purified State: Lyphilized purified Ig fraction |
Reconstitution Method | Restore with 1.2% sodium acetate or neutral PBS |
Concentration | 0,1 mg/ml (after reconstitution with PBS) |
Purification | Affinity chromatography |
Conjugation | Unconjugated |
Storage | Prior to reconstitution store at -20°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Shipping | Ambient |
Gene Name | nebulin |
Database Link | |
Background | Nebulin is a giant protein component of the cytoskeletal matrix that coexists with the thick and thin filaments within the sarcomeres of skeletal muscle. In most vertebrates, nebulin accounts for 3 to 4% of the total myofibrillar protein and its size varies from 600 to 800 kD in a manner that is tissue-, species-,and developmental stage-specific. The nebulin gene contains 183 exons in a 249-kb genomic region. Nebulin is mapped to chromosome 2. Nebulin is a giant filamentous protein specific for vertebrate skeletal muscles. Mutations in the nebulin gene associated with autosomal recessive nemaline myopathy. |
Synonyms | NEB |
Reference Data |
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