Aggrecan Mouse Monoclonal Antibody [Clone ID: 4G4/A10]
| Product Data | |
| Clone Name | 4G4/A10 |
|---|---|
| Application | ELISA, IHC, WB |
| Recommended Dilution | ELISA: Less than 1 µg/ml (Ref.1) Western Blot: 1 µg/ml Immunohistochemistry: 1 µg/ml |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Purified Human Aggrecan |
| Specificity | Monoclonal Ab 4G4/A10 is specific for a core protein epitope of Human articular cartilage. Therefore, in addition to applications in immunochemistry and immunohistochemistry, the 4G4/A10 monoclonal antibody can be used for the detection of aggrecan core protein fragments released during Human inflammatory or degenerative joint diseases into synovial fluid and serum. |
| Buffer | 50 mM TRIS pH 7.4 without preservatives State: Purified State: Lyophilized purifed Cell Culture Supernatant |
| Reconstitution Method | Restore in aqua bidest to 1 mg/ml. |
| Purification | Protein G Chromatography |
| Conjugation | Unconjugated |
| Storage | Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Gene Name | aggrecan |
| Database Link | |
| Background | Aggrecan is the major proteoglycan of human articular cartilage. The core protein is substituted by a number of keratan sulfate and chondroitin sulfate glycosaminoglycan chains. |
| Synonyms | ACAN, AGC1, CSPG1, MSK16 |
| Reference Data | |
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