PDGF Receptor alpha (PDGFRA) Mouse Monoclonal Antibody [Clone ID: 16A1]

CAT#: AM12068BT-N

PDGF Receptor alpha (PDGFRA) mouse monoclonal antibody, clone 16A1, Biotin

Conjugation: Unconjugated APC Biotin PE


USD 310.00

2 Weeks*

Size
    • 100 ug

Product Images

Other products for "PDGF Receptor alpha"

Specifications

Product Data
Clone Name 16A1
Applications FC
Recommended Dilution Indirect immunofluorescence analysis by Flow cytometry: 3 μg/ml as starting dilution.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen CD140a-transfected NIH 3T3 cells
Specificity The antibody recognizes CD140a / PDGF-RA, the 170 kDa alpha chain of platelet-derived growth factor receptor, which is widely expressed on a variety of mesenchymal-derived cells and plays pro-proliferative or anti-proliferative roles in various tumours.
Formulation Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Label: Biotin
State: Liquid purified Ig fraction
Label: Conjugated with -LC-NHS under optimum conditions. The reagent is free of unconjugated biotin
Concentration lot specific
Conjugation Biotin
Storage Store the antibody undiluted at 2 - 8 °C. DO NOT FREEZE!
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens platelet-derived growth factor receptor, alpha polypeptide (PDGFRA)
Background CD140a / PDGF-RA (platelet-derived growth factor receptor alpha) is a cell surface receptor for members of platelet-derived growth factor family, whose intracellular part contains a tyrosine kinase domain. CD140a forms homodimers, or heterodimerizes with CD140b / PDGF-RB. Whereas CD140b induces in different cell types their proliferation and migration, the role of CD140a is more controversial, with pro-proliferative or anti-proliferative effects. CD140a has early developmental functions, mediates mesodermal cell migration, and later acts in signaling associated in epithelial-mesenchymal interactions.
Synonyms PDGF-R-alpha, PDGF Receptor alpha
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase, Transmembrane
Protein Pathways Calcium signaling pathway, Colorectal cancer, Cytokine-cytokine receptor interaction, Endocytosis, Focal adhesion, Gap junction, Glioma, MAPK signaling pathway, Melanoma, Pathways in cancer, Prostate cancer, Regulation of actin cytoskeleton

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.