BCL2 (1-211) Mouse Monoclonal Antibody [Clone ID: AT1B5]

CAT#: AM09378PU-N

BCL2 (1-211) mouse monoclonal antibody, clone AT1B5, Purified

Size: 50 ul 100 ul


USD 426.00

3 Weeks*

Size
    • 100 ul

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Other products for "BCL2"

Specifications

Product Data
Clone Name AT1B5
Applications ELISA, FC, IF, WB
Recommended Dilution ELISA.
Western blot (1:250 - 1:500).
Immunofluorescence (1:250 - 1:500).
Flow cytometry.
Reactivities Human, Mouse
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Recombinant human Bcl-2 (1-211aa) purified from E. coli
Specificity The antibody recognizes Bcl-2 (B-cell lymphoma protein 2 alpha) at aa 1-211.
Formulation PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol
State: Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Protein-G affinity chromatography
Conjugation Unconjugated
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens B-cell CLL/lymphoma 2 (BCL2), transcript variant alpha
Background Bcl-2 (B-cell lymphoma protein 2 alpha) is an anti-apoptotic protein located primarily in the outer mitochondrial membrane. It blocks the apoptotic death of some cells such as lymphocytes. BCL-2 is thought to regulate cell death by controlling the mitochondrial membrane permeability during apoptosis. Bcl-2 protein has anti-apoptotic functions through inhibiting caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
Synonyms BCL2, Bcl-2 alpha
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Stem cell - Pluripotency, Transmembrane
Protein Pathways Amyotrophic lateral sclerosis (ALS), Apoptosis, Colorectal cancer, Focal adhesion, Neurotrophin signaling pathway, Pathways in cancer, Prostate cancer, Small cell lung cancer

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.