HAX1 Mouse Monoclonal Antibody [Clone ID: AT3C5]
Specifications
| Product Data | |
| Clone Name | AT3C5 |
|---|---|
| Application | ELISA, ICC/IF, WB |
| Recommended Dilution | ELISA. Western blot (1:1000 - 1:2000). |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG2b, kappa |
| Clonality | Monoclonal |
| Immunogen | Recombinant human HAX1 (1-279aa) purified from E. coli |
| Specificity | The antibody recognizes human HAX-1. Other species not tested. |
| Buffer | Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol |
| Concentration | 1mg/ml (determined by BCA assay) |
| Purification | By protein-G affinity chromatography |
| Conjugation | Unconjugated |
| Storage | Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | HCLS1 associated protein X-1 |
| Database Link | |
| Background | HAX1 is known to associate with hematopoietic cell-specific Lyn substrate 1 (HS1), one of the substrates of receptor-coupled tyrosine kinases activated during clonal expansion and deletion in lymphoid cells. It also interacts with the product of the polycystic kidney disease 2 (PKD2) gene and with the F-actin-binding protein, cortactin. HAX1 is also reported to bind to hairpin structures in vimentin and DNA polymerase beta mRNAs, so may play a role in mRNA stability and transport. It may also function in promoting cell survival. Defects in HAX1 are the cause of autosomal recessive severe congenital neutropenia 3 (SCN3) also called Kostmann disease. |
| Synonyms | HCLS1 associated protein X-1, HS1BP1, HCLSBP1, HCLS1 (and PKD2) associated protein |
| Reference Data | |
| Protein Categories | Cytokines, Immune system diseases, Intracellular Proteins |
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.