CD15 Mouse Monoclonal Antibody [Clone ID: HI98]
Specifications
| Product Data | |
| Clone Name | HI98 |
|---|---|
| Application | FC, IHC |
| Recommended Dilution | Flow Cytometry. Immunohistochemistry on Frozen Sections. Immunohistochemistry on Paraffin Sections: 1/50. |
| Reactivity | Chimpanzee, Human |
| Antibody Host | Mouse |
| Isotype | IgM |
| Clonality | Monoclonal |
| Immunogen | Human PBMCs |
| Specificity | This antibody reacts to Human Fucosyltransferase 4 (alpha (1,3) Fucosyltransferase, Myeloid-specific) (FUT4/CD15). |
| Buffer | PBS, pH 7.2 containing 0.09% Sodium Azide State: Purified State: Liquid purified Ig fraction |
| Concentration | lot specific |
| Purification | Affinity Chromatography |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Background | The CD15 antigen is expressed on approximately 90% human circulating granulocytes (membranes and granules), 30 to 60% of circulating monocytes and is absent from normal lymphocytes. CD15 antigen is also expressed on Reed Sternberg cells of Hodgkin's disease, on T cell lymphomas including mycosis fungoides and on some leukemias. Outside the hematopoietic system, CD15 expression is described in certain normal and neoplastic epithelial cells and in astrocytes. At least 5 major CD15 antigens (105, 135, 165, 185, 220 kDa) are present on the surface membranes of polymorphonuclear cells. The hapten occurs also in glycolipids. CD15 plays a role in mediating phagocytosis, bactericidal activity and chemotaxis. |
| Synonyms | Lewis X, X-Hapten, Lacto-N-Fucopentaose III, Stage-Specific Embryonic Antigen, SSEA1 |
| Reference Data | |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |