CD51 (ITGAV) Mouse Monoclonal Antibody [Clone ID: 13C2]
$280.00
3 Days*
Specifications
| Product Data | |
| Clone Name | 13C2 |
|---|---|
| Application | FC, IHC |
| Recommended Dilution | Flow Cytometry: ≤ 1 µg/106 cells (Reported in literature 7,9,10). Immunohistochemistry on Frozen Sections (Reported in literature 1,5). Immunocytochemistry (Reported in literature 3). Immunoprecipitation (Reported in literature 2,3,5,9). ELISA (Reported in literature 8). Purification (Reported in literature 4,5). Depletion (Reported in literature 7). Blocking (Reported in literature 3,6). Adhesion (Reported in literature 3). |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Cell suspension containing osteoclasts from osteoclastomas. |
| Specificity | This antibody recognizes CD51. |
| Buffer | 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added. State: Purified State: Liquid purified Ig fraction. |
| Concentration | lot specific |
| Conjugation | Unconjugated |
| Storage | Store undiluted at 2-8°C. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | integrin subunit alpha V |
| Database Link | |
| Background | Integrin alpha V chain interacts with the integrin beta 3 subunit/CD61 to form the alpha-V-beta-3 heterodimer/vitronectin receptor. It is expressed on endothelial cells, some activated leukocytes, NK cells, macrophages, neutrophils, and platelets. Integrin alpha V also forms heterodimers with the integrin beta 1, beta 5, beta 6, and beta 8 subunits. Alpha-V-beta-3 is an activation dependent receptor for platelet attachment and spreading on vitronectin and other matrix components. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. Alpha-V/beta-6 binds to foot-and-mouth disease virus (FMDV) VP1 protein and acts as a receptor for this virus By similarity. Alpha-V/beta-6 binds to coxsackievirus A9 and coxsackievirus B1 capsid proteins and acts as a receptor for these viruses. It also mediates leukocyte-endothelial cell adhesion via interaction with CD31. (Ref.1-4) |
| Synonyms | Integrin alpha-V, MSK8, VNRA, Vitronectin receptor subunit alpha |
| Reference Data | |
| Protein Categories | ADC Targets, CD Markers, Chemokines, Growth Factors, Intracellular Proteins, Membrane Proteins |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.