CD8B Mouse Monoclonal Antibody [Clone ID: EP42]
Specifications
| Product Data | |
| Clone Name | EP42 |
|---|---|
| Application | FC, IHC, IP |
| Recommended Dilution | Flow Cytometry. (Ref.2) Immunoprecipitation. (Ref.2) Immunohistochemistry (Acetone-Fixed, Frozen Tissue Sections. (Ref.4) |
| Reactivity | Chicken |
| Antibody Host | Mouse |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Specificity | This antibody recognizes beta chain of Chicken CD8 (Mr. 34 kDa). |
| Buffer | 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added. State: Purified State: Liquid purified Ig fraction. |
| Concentration | lot specific |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | CD8b molecule |
| Database Link | |
| Background | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. Chicken CD8 is expressed on approximately 80% of thymocytes, 45% of blood mononuclear cells and 50% of spleen cells, but <1% of cells in the bursa and bone marrow. (Ref.1,2) |
| Synonyms | CD8B, CD8B1 |
| Reference Data | |
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