CD8 Mouse Monoclonal Antibody [Clone ID: CT-8]
Specifications
| Product Data | |
| Clone Name | CT-8 |
|---|---|
| Application | FC |
| Recommended Dilution | Flow Cytometry (≤ 1 µg/106 cells): Identification and enumeration of CD8+cells. (Ref.2) |
| Reactivity | Chicken |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Specificity | This antibody recognizes alpha chain (34-kDa) of Chicken CD8. |
| Buffer | PBS containing 0.09% Sodium Azide as preservative. Label: Cy5 State: Liquid purified Ig fraction. Label: Cyanine 5 |
| Concentration | lot specific |
| Conjugation | Cy5 |
| Storage | Store the antibody undiluted at 2-8°C for one month or in (aliquots) at -20°C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Database Link | |
| Background | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. CD8 is expressed on most thymocytes and approximately 1/3 of peripheral blood T cells in humans. CD8 alpha/beta heterodimers are expressed only on TCR alpha/beta T cells, whereas CD8 alpha homodimers can be expressed on alpha/beta and gamma/delta T cells and some NK cells in humans. The pattern of expression in other species has not been well documented. |
| Synonyms | CD8 alpha chain, CD8A, MAL |
| Reference Data | |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.