CD8A Mouse Monoclonal Antibody [Clone ID: fCD8]
Specifications
| Product Data | |
| Clone Name | fCD8 |
|---|---|
| Application | FC |
| Recommended Dilution | Flow Cytometry: 1 µg/10e6 cells. (Ref.1-2) Immunohistochemistry on frozen tissue sections. Immunoprecipitation. |
| Reactivity | Feline |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Specificity | This antibody recognizes Feline CD8 (Mr. 70 kDa) (38/31 kDa under reducing conditions). |
| Buffer | PBS/NaN3 Label: Biotin State: Liquid purified Ig fraction |
| Concentration | lot specific |
| Conjugation | Biotin |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Database Link | |
| Background | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. |
| Synonyms | CD8 alpha chain, CD8A, MAL |
| Note | U.S. Patent 4,520,110; European Patent No. 76,695; and Canadian Patent No. 1,179,942. FACScanTM is a registered trademark of Becton Dickinson Immunocytometry Systems, Inc., San Jose, CA. |
| Reference Data | |
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