CD8A Mouse Monoclonal Antibody [Clone ID: 76-2-11]
$690.00
3 Days*
Specifications
| Product Data | |
| Clone Name | 76-2-11 |
|---|---|
| Application | CT, FC, IHC, IP |
| Recommended Dilution | Flow Cytometry – Quality tested 1,11-15,17-28
Immunohistochemistry-Frozen Sections – Reported in literature 2-6,16Immunohistochemistry-Paraffin Sections – Reported in literature 7 Immunoprecipitation – Reported in literature 1 Blocking – Reported in literature 8,9 Depletion – Reported in literature 10 Complement Mediated Cell Depletion – Reported in literature 1 |
| Reactivity | Porcine |
| Antibody Host | Mouse |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Immunogen | Fresh dd miniature swine thymocytes |
| Specificity | This antibody reacts with Porcine CD8 alpha (Mr. 32-34 kDa). (Ref-1-3) |
| Buffer | 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added. State: Purified State: Liquid purified Ig fraction. |
| Concentration | lot specific |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Database Link | |
| Background | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. CD8 is expressed on most thymocytes and approximately 1/3 of peripheral blood T cells in humans. CD8 alpha/beta heterodimers are expressed only on TCR alpha/beta T cells, whereas CD8 alpha homodimers can be expressed on alpha/beta and gamma/delta T cells and some NK cells in humans. The pattern of expression in other species has not been well documented. |
| Synonyms | CD8 alpha chain, CD8A, MAL |
| Reference Data | |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.