Cd79b Hamster Monoclonal Antibody [Clone ID: HM79-12]
Specifications
| Product Data | |
| Clone Name | HM79-12 |
|---|---|
| Application | FC, IHC, IP, WB |
| Recommended Dilution | Flow Cytometry: < / = 1 µg/10e6 cells. (Ref.1,2) Immunoprecipitation. (Ref.1) Immunohistochemistry on Frozen Sections. (Ref.3) Western Blotting. (Ref.1) |
| Reactivity | Mouse |
| Antibody Host | Hamster |
| Isotype | IgG |
| Clonality | Monoclonal |
| Specificity | This antibody recognises beta chain of the mouse B-cell receptor (Mr. 23 kDa). |
| Buffer | 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added. State: Purified State: Liquid purified Ig fraction. |
| Concentration | lot specific |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | CD79B antigen |
| Database Link | |
| Background | Murine CD79 is a 23/21 kDa disulfide-linked heterodimer composed of an alpha chain (CD79a/mb-1) and a beta chain (CD79b/B29) that associates non-covalently with membrane immunoglobulin (Ig) to form the B cell receptor (BCR) complex. Its expression is restricted to B lymphocytes, first appearing on the surface at the pro-B cell stage prior to productive Ig gene rearrangements and remaining through all stages of B-cell differentiation prior to plasma cells. It has been proposed that the CD79 complex on pro-B cell surfaces may function to induce early B-cell differentiation. (Ref.1) |
| Synonyms | B29, IGB, B-Cell marker |
| Reference Data | |
| Protein Categories | ADC Targets, Cancer: Haematopoietic and Lymphoid, CD Markers, Immune system diseases, Membrane Proteins |
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