Klra6 Mouse Monoclonal Antibody [Clone ID: HBF-719]
Specifications
| Product Data | |
| Clone Name | HBF-719 |
|---|---|
| Application | FC |
| Recommended Dilution | Flow Cytometry: < / = 1 µg/10e6 cells. (Ref.1,3) |
| Reactivity | Mouse |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | CHO cells transfected with the B6 allele of Ly49F. (Ref.1) |
| Specificity | This antibody HBF-719 reacts with the B6 allele of Ly49F. It stains ~ 11% of NK1.1+CD3- splenocytes, and 3.5% (2.5 month old) to 10.0% (11 month old) of CD8+ spleen cells from C57BL/6 mice. (Ref.1) |
| Buffer | PBS containing 0.09% Sodium Azide as preservative. Label: FITC State: Liquid purified Ig fraction. Label: Fluorescein Isothiocyanate Isomer 1 |
| Concentration | lot specific |
| Conjugation | FITC |
| Storage | Store the antibody undiluted at 2-8°C for one month or in (aliquots) at -20°C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | killer cell lectin-like receptor, subfamily A, member 6 |
| Database Link | |
| Background | Ly49F is a member of the lectin like homodimeric Ly49 family of cell surface receptors. (Ref.1) Mouse Ly49 receptors exhibit allelic specificity for MHC class I Ia molecules and are thought to serve to prevent natural killer (NK) cells from attacking normal cells, while allowing them to attack infected or transformed cells in which class I molecules have been down regulated. (Ref.2) These inhibitory receptors are also expressed on a subpopulation of mouse CD8+ T cells. |
| Synonyms | Ly-49f, Ly49-f, Ly49F |
| Reference Data | |
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