Klra3 Hamster Monoclonal Antibody [Clone ID: 14B11]
$455.00
3 Days*
Specifications
| Product Data | |
| Clone Name | 14B11 |
|---|---|
| Application | FC |
| Recommended Dilution | Flow Cytometry: < / = 1 µg/10e6 cells. (Ref.1,3) |
| Reactivity | Mouse |
| Antibody Host | Hamster |
| Isotype | IgG |
| Clonality | Monoclonal |
| Specificity | This antibody is specific to an epitope common to the Ly49C, Ly49F, Ly49H and Ly49I allelic/splice variants. The antibody stains ~ 90% of NK1.1+CD3- splenocytes, and ~ 6% of CD8+ spleen cells from C57BL/6 mice. (Ref.1) The antibody also stains 30-80% of NK1.1+CD3-splenocytes in other mouse strains tested (BALB/c, C3H, 129, SJL, AKR/J). |
| Buffer | 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added. State: Purified State: Liquid purified Ig fraction. |
| Concentration | lot specific |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | killer cell lectin-like receptor, subfamily A, member 3 |
| Database Link | |
| Background | Ly49C, Ly49F, Ly49H and Ly49I are members of the lectin like homodimeric Ly49 family of cell surface receptors. Mouse Ly49 receptors exhibit allelic specificity for MHC class I Ia molecules and are thought to serve to prevent natural killer (NK) cells from attacking normal cells, while allowing them to attack infected or transformed cells in which class I molecules have been down regulated. (Ref.2) These inhibitory receptors are also expressed on a subpopulation of mouse CD8+ T cells. |
| Synonyms | Ly49C, Ly49F, Ly49H, Ly49I, Ly-49H, Ly-49C, Ly-49F, Ly-49I, Klra3, Klra9, Klra8, Klra6 |
| Reference Data | |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.