Cd72 (CD72.1 alloantigen) Mouse Monoclonal Antibody [Clone ID: 10-1.D.2]
Specifications
| Product Data | |
| Clone Name | 10-1.D.2 |
|---|---|
| Application | FC |
| Recommended Dilution | Flow Cytometry: < / = 1 µg/10e6 cells. (Ref.1,2) |
| Reactivity | Mouse |
| Antibody Host | Mouse |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Immunogen | DBA/2 mouse spleen cells. (Ref.1) |
| Specificity | This antibody recognises CD72.1/Lyb-2.1 (Mr. 45 kDa). |
| Buffer | PBS containing 0.09% Sodium Azide as preservative. Label: Biotin State: Liquid purified Ig fraction. |
| Concentration | lot specific |
| Conjugation | Biotin |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | CD72 antigen |
| Database Link | |
| Background | Murine CD72.1/Lyb-2.1, a type II integral membrane glycoprotein and a member of the C-lectin family of cell surface receptors, is a differentiation antigen of B cells, and is found in mouse strains expressing the Lyb-2.1 allotype. CD72.1 is the ligand of CD5 (Ly-1) which is distributed on all T cells and a small number of B cells. (Ref.1,2) This clone blocks binding of CD5 to CD72 on the B cell surface, which leads to inhibition of the positive signal resulting from CD5/CD72 pairing. (Ref.1) However, 10-1.D.2 can itself trigger a positive signal by binding CD72. (Ref.1-5) |
| Synonyms | Lyb-2, Ly-32, Ly32, B-Cell marker |
| Reference Data | |
| Protein Categories | CD Markers, Intracellular Proteins, Membrane Proteins |
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