Cd3e Rat Monoclonal Antibody [Clone ID: C363.29B (YCD3-1)]
$470.00
2 Weeks*
Specifications
| Product Data | |
| Clone Name | C363.29B (YCD3-1) |
|---|---|
| Application | FC, FN, IHC, IP |
| Recommended Dilution | Flow Cytometry: Identification and enumeration of CD3+ cells (< / = 3 µg/10e6 cells). (Ref.1-2) Immunoprecipitation. (Ref.1) Functional Assay: In vitro Depletion of CD3+ cells. (Ref.1) In vitro Activation of T cells (accessory cells must be provided). (Ref.1,3,4) Immunohistochemistry. (Ref.5) |
| Reactivity | Mouse |
| Antibody Host | Rat |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Specificity | This antibody is specific to CD3e (Mr. 25 kD). The monoclonal antibody C363.29B recognizes an epitope on the 25kD epsilon chain of the CD3/TCR complex. (Ref.1) In the presence of Fc receptor-bearing accessory cells, soluble C363.29B can activate primed and naïve T cell in vitro. Immobilized C363.29 monoclonal antibody can also activate both normal T lymphocytes and cloned T cell lines provided the appropriate accessory signals are present. (Ref.1,3,4) The monoclonal antibody is cytolytic, easily used for cell surface staining and a good immunoprecipitating antibody. (Ref.1) |
| Buffer | PBS containing 0.09% Sodium Azide as preservative. Label: Biotin State: Liquid purified Ig fraction. |
| Concentration | lot specific |
| Conjugation | Biotin |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | CD3 antigen, epsilon polypeptide |
| Database Link | |
| Background | CD3e, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chain ranging in size from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). It is expressed on all T cells of all mouse strains. (Ref.1,2) CD3 plays a major role in signaling during antigen recognition, leading to T-cell activation. |
| Synonyms | T3/Leu-4 |
| Reference Data | |
| Protein Categories | ADC Targets, CD Markers, Immune system diseases, Membrane Proteins |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.