Ubiquitin(UBB) Mouse Monoclonal Antibody [Clone ID: 3C12]

CAT#: AM06722PU-N

Mouse Monoclonal Anti-UBB Antibody, Purified


 Product Datasheet for 'AM06722PU-N'

USD 410.00


Availability*
2 Weeks

Size
    • 0.1 mg


Product images

Specifications

Product Data
Clone Name 3C12
Applications WB, ELISA, FC
Recommend Dilution ELISA, FC, WB
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Purified recombinant fragment of Human UBB expressed in E. Coli.
Isotype IgG1
Formulation PBS
Concentration 1.0 mg/ml
Purification Liquid purified antibody
Purified
Predicted Protein Size 25.6KDa
Gene Name ubiquitin B
Background This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome.
Synonyms HEL-S-50
Reference Data
Protein Families Druggable Genome
Protein Pathways Parkinson's disease
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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