MMP1 Mouse Monoclonal Antibody [Clone ID: 6A5]
Specifications
| Product Data | |
| Clone Name | 6A5 |
|---|---|
| Application | ELISA, FC, IF, IHC, WB |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry on paraffin sections: 1/200 - 1/1000. Immunofluorescence: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Purified recombinant fragment of human MMP1 expressed in E. Coli. |
| Specificity | This antibody reacts to MMP1. |
| Buffer | State: Ascites State: Ascitic fluid containing 0.03% sodium azide. |
| Conjugation | Unconjugated |
| Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | 54 kDa |
| Gene Name | matrix metallopeptidase 1 |
| Database Link | |
| Background | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants. |
| Synonyms | Interstitial collagenase, Matrix metalloproteinase-1, Fibroblast collagenase, MMP1, CLG |
| Reference Data | |
| Protein Categories | Cancer: Gynecologic, Enzyme: Peptidases, Secreated Proteins |
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