Osteoprotegerin (TNFRSF11B) Mouse Monoclonal Antibody [Clone ID: 5G2]
$580.00
2 Weeks*
Specifications
| Product Data | |
| Clone Name | 5G2 |
|---|---|
| Application | ELISA, FC, IF, WB |
| Recommended Dilution | ELISA: 1/10000. Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. Flow Cytometry: 1/200 - 1/400. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Purified recombinant fragment of Human TNFRSF11B expressed in E. Coli. |
| Specificity | Recognizes Osteoprotegerin / TNFRSF11B |
| Buffer | State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide. |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | 60 kDa |
| Gene Name | tumor necrosis factor receptor superfamily member 11b |
| Database Link | |
| Background | The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. |
| Synonyms | OPG, OCIF |
| Reference Data | |
| Protein Categories | Cytokines, Secreated Proteins |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.