TrkC (NTRK3) Mouse Monoclonal Antibody [Clone ID: 4G5]

CAT#: AM06365SU-N

TrkC (NTRK3) mouse monoclonal antibody, clone 4G5, Ascites

Product Images

Western blot analysis using NTRK3 mouse mAb against extracellular domain of human NTRK3 (aa32-429).

Specifications

Product Data

• Clone Name: 4G5
• Applications: WB
• Recommended Dilution: Western Blot: 1/500 - 1/2000.
  ELISA: 1/10000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant extracellular fragment of human NTRK3 (aa32-429) fused with hIgGFc tag expressed in HEK293 cells.
• Specificity: This antibody reacts to NTRK3.
• Formulation: State: Ascites
  State: Ascitic fluid containing 0.03% sodium azide.
• Conjugation: Unconjugated
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 94 kDa
• Gene Name: neurotrophic receptor tyrosine kinase 3
• Database Link:
  Entrez Gene 4916 Human
  UniProt ID Q16288
• Background: NTRK3 (neurotrophic tyrosine kinase, receptor, type 3), it is a member of the neurotrophic tyrosine receptor kinase (NTRK) family and plays an important role in the development and maintenance of neural tissues. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.
• Synonyms: NTRK3