AXL Mouse Monoclonal Antibody [Clone ID: 7E10]
Product Data | |
Clone Name | 7E10 |
---|---|
Application | ELISA, IF, WB |
Recommended Dilution | ELISA: 1/10000. Western Blot: 1/500-1/2000. Immunofluorescence: 1/200-1/1000. |
Reactivity | Human |
Antibody Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Purified recombinant extracellular fragment of Human AXL fused with hIgGFc tag expressed in HEK293 cell line. |
Specificity | Recognizes AXL receptor tyrosine kinase |
Buffer | State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide. |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Predicted Protein Size | 97.4 kDa |
Gene Name | AXL receptor tyrosine kinase |
Database Link | |
Background | AXL receptor tyrosine kinase, also known as UFO, JTK11 is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified. |
Synonyms | JTK11; UFO |
Reference Data |
Write Your Own Review
Product Manuals |
FAQs |
SDS |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.