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Factor VIII (F8) Mouse Monoclonal Antibody [Clone ID: 5E9B2]

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SKU
AM06283SU-N
Factor VIII (F8) mouse monoclonal antibody, clone 5E9B2, Ascites
Size:
100 ul
Conjugation:
Unconjugated
  $580.00
2 Weeks*
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View other "F8 or NP_000123.1" antibodies

Specifications
Specifications
Product Data
Clone Name 5E9B2
Application WB
Recommended Dilution ELISA: 1/10000.
Western Bloting: 1/500 - 1/2000.
Reactivity Human
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Purified recombinant fragment of F8 expressed in E. Coli.
Specificity Recognizes Coagulation factor VIII (F8).
Buffer State: Ascites
State: Ascitic fluid containing 0.03% Sodium Azide.
Conjugation Unconjugated
Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Gene Name coagulation factor VIII
Database Link
Background This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.
Synonyms Procoagulant component, Antihemophilic factor, F8C, AHF
Reference Data
Protein Categories Cardiovascular diseases, Intracellular Proteins, Secreated Proteins
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.