PARL Mouse Monoclonal Antibody [Clone ID: 8C4B2]
Specifications
| Product Data | |
| Clone Name | 8C4B2 |
|---|---|
| Application | ELISA, WB |
| Recommended Dilution | ELISA: 1/10000. Western Blot: 1/500 - 1/2000. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Immunogen | Purified recombinant fragment of PARL (aa112-167) expressed in E. Coli. |
| Specificity | Recognizes PARL (presenilin associated, rhomboid-like). |
| Buffer | State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide. |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | presenilin associated rhomboid like |
| Database Link | |
| Background | This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Synonyms | PSARL, PRO2207 |
| Reference Data | |
| Protein Categories | Enzyme: Peptidases, Intracellular Proteins, Membrane Proteins |
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