SRC Mouse Monoclonal Antibody [Clone ID: 5D10C4]
Specifications
| Product Data | |
| Clone Name | 5D10C4 |
|---|---|
| Application | WB |
| Recommended Dilution | ELISA: 1/10000. Western Blotting: 1/500 - 1/2000. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Immunogen | Purified recombinant fragment of SRC (aa10-193) expressed in E. Coli. |
| Specificity | Recognizes SRC: v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian). |
| Buffer | State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide. |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | SRC proto-oncogene, non-receptor tyrosine kinase |
| Database Link | |
| Background | This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. |
| Synonyms | c-Src, pp60c-src |
| Reference Data | |
| Protein Categories | Cardiovascular diseases, Cytokines, Enzyme: Kinases, Growth Factors, Intracellular Proteins |
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