S100A1 Mouse Monoclonal Antibody [Clone ID: 2C8B8]

CAT#: AM06160SU-N

S100A1 mouse monoclonal antibody, clone 2C8B8, Ascites

Product Images

Western blot analysis using S100A antibody Cat.-No AM06160SU-N against truncated S100A recombinant protein.

• 

  Immunohistochemical analysis of paraffin-embedded human brain tissue (A), lymphoid follicles tissue (B) and interbrain tissue (C), showing cytoplasmic localization using S100A antibody Cat.-No AM06160SU-N with DAB staining.

Specifications

Product Data

• Clone Name: 2C8B8
• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/10000.
  Western Blot: 1/500 - 1/2000.
  Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000.
  
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of S100A1 expressed in E. Coli.
• Specificity: Recognizes S100 calcium binding protein A1 (S100-alpha/ S100A1).
• Formulation: State: Ascites
  State: Ascitic fluid
  Preservative: 0.03% Sodium Azide
• Conjugation: Unconjugated
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: S100 calcium binding protein A1
• Database Link:
  Entrez Gene 6271 Human
  UniProt ID P23297
• Background: S100 calcium binding protein A1 (S100-alpha/ S100A1), it is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.
• Synonyms: S100-A1, S100A, S100 alpha, S100 calcium-binding protein A1, S-100 protein subunit alpha, S-100 protein alpha chain