Desmin (DES) Mouse Monoclonal Antibody [Clone ID: 10H7D2]

SKU AM06142PU-N

Desmin (DES) mouse monoclonal antibody, clone 10H7D2, Purified

Product Data

• Clone Name: 10H7D2
• Application: ELISA, IHC, WB
• Recommended Dilution: ELISA: 1/10000.; Western Blot: 1/500 - 1/2000.; Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000.
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of Desmin expressed in E. Coli.
• Specificity: Recognizes Desmin (DES).
• Buffer: PBS; State: Purified; State: Liquid purified IgG fraction; Preservative: 0.03% Sodium Azide
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: desmin
• Database Link:
  P17661
• Background: Desmin (DES), with 470-amino acid protein (about 52kDa), belongs to the intermediate filament family and Desmin is class III intermediate filaments found in muscle cells. Homopolymers of Desmin form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane.Mutations in Desmin are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.Desmin is also expressed in smooth muscle cells of both airways and alveolar ducts and Desmin is a load-bearing protein that stiffens the airways and consequently the lung and modulates airway contractile response.
• Synonyms: DES

Reference Data