Eph receptor A2 (EPHA2) Mouse Monoclonal Antibody [Clone ID: 1B3C7]
$580.00
2 Weeks*
Specifications
| Product Data | |
| Clone Name | 1B3C7 |
|---|---|
| Application | IHC, WB |
| Recommended Dilution | ELISA: 1/10000. Western Blot: 1/500 - 1/2000. Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgM |
| Clonality | Monoclonal |
| Immunogen | Purified recombinant fragment of EphA2 expressed in E. Coli. |
| Specificity | Recognizes EPH receptor A2 (EphA2) |
| Buffer | State: Ascites State: Ascitic fluid Preservative: 0.03% Sodium Azide |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | EPH receptor A2 |
| Database Link | |
| Background | EPH receptor A2 (EphA2), with 976-amino acid protein (about 107 kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EphA1, EphA2, EphA3, EphA4, EphA5, EphA6, EphA7, EphA8, EphA10, EphB1, EphB2, EphB3, EphB4 and EphB6 are Eph family receptors for Ephrin family ligands. In normal cells, EphA2 negatively regulates cell growth and invasiveness. EphA2 is overexpressed by many human cancers, and is often associated with poor prognostic features. The clinical significance of the expression of EphA2 was observed in breast, prostate, colon, skin, cervical, ovarian, and lung cancers. EphA2 may serve as a novel target for bladder cancer, colonic adenocarcinoma and ovarian cancer therapy. |
| Synonyms | Ephrin type-A receptor 2, Epithelial cell kinase, Eph receptor A2 |
| Reference Data | |
| Protein Categories | ADC Targets, Chemokines, Cytokines, Enzyme: Kinases, Growth Factors, Membrane Proteins, Nervous system Diseases |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.