EHMT1/GLP (EHMT1) Mouse Monoclonal Antibody [Clone ID: 1B7B4]
$510.00
2 Weeks*
Specifications
| Product Data | |
| Clone Name | 1B7B4 |
|---|---|
| Application | ELISA, WB |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Purified recombinant fragment of GLP expressed in E. Coli. |
| Specificity | This antibody reacts to GLP. |
| Buffer | PBS State: Purified State: Liquid purified Ig fraction Preservative: 0,03% sodium azide |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | euchromatic histone lysine methyltransferase 1 |
| Database Link | |
| Background | Glucagon-like peptide-1 (GLP-1) is an incretin hormone secreted from enteroendocrine L cells in response to ingested nutrients. The closely related peptides glucagon-like peptide (GLP-1) and glucagon have opposing effects on blood glucose. GLP-1 induces glucose-dependent insulin secretion in the pancreas, while glucagon stimulates gluconeogenesis and glycogenolysis in the liver. Glucagon is processed from a large precursor, proglucagon, in a tissue-specific manner in pancreatic alpha-cells. The identification of a hybrid peptide acting as both a GLP-1 agonist and a glucagon antagonist would provide a novel approach for the treatment of type 2 diabetes. |
| Synonyms | EUHMTASE1, GLP, KIAA1876, KMT1D, Eu-HMTase1, G9a-like protein 1, GLP, GLP1, H3-K9-HMTase 5 |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.