Cardiac Troponin I (TNNI3) Mouse Monoclonal Antibody [Clone ID: 3A10A12]
CAT#: AM06110SU-N
Cardiac Troponin I (TNNI3) mouse monoclonal antibody, clone 3A10A12, Ascites
Other products for "TNNI3"
Specifications
Product Data | |
Clone Name | 3A10A12 |
Applications | ELISA, IHC, WB |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry on paraffin sections: 1/200 - 1/1000. ELISA: 1/10000. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Purified recombinant fragment of cTnI expressed in E. Coli. |
Specificity | This antibody reacts to cTnl. |
Formulation | State: Ascites State: Ascitic fluid containing 0.03% sodium azide. |
Conjugation | Unconjugated |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Gene Name | troponin I3, cardiac type |
Database Link | |
Background | cTnI has an apparent molecular weight of 22.5 kDa. cTnI is a candidate marker with acceptable sensitivity and specificity for AMI and other cardiac diseases. Troponin, a molecule that binds to the thin filament (actin) of striated muscle fibers, acts with intracellular calcium to control the interaction of the thin filament with the thick filament (myosin), thus regulating muscle contraction. Troponin I prevents muscle contraction in the absence of calcium, which has two skeletal muscle isoforms with considerable amino acid sequence homology. cTnI contains an additional N-terminal sequence and is highly specific for myocardium. |
Synonyms | TNNI3, TNNC1 |
Reference Data |
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