Rituximab Rat Monoclonal Antibody [Clone ID: MB2 A4]

CAT#: AM05879FC-N

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Rituximab rat monoclonal antibody, clone MB2 A4, FITC

 Product Datasheet for 'AM05879FC-N'

  View other "MB2 A4" antibodies (2)

USD 900.00

5 Days

    • 100 ug

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Product Data
Clone Name MB2 A4
Applications FC
Recommend Dilution Flow Cytometry: Use 10 µl of neat antibody to label 106 cells in 100 µl.
Host Rat
Isotype IgG2a
Clonality Monoclonal
Immunogen F(ab)2 fragment of Rituximab
Specificity This antibody specifically recognizes the idiotypic determinants expressed by the Rituximab humanised monoclonal antibody. This antibody does not recognise other CD20 antibodies.
It has been used to detect Rituximab bound to the surface of the Raji B cell line, however detection of Rituximab bound 'in vivo' to B-CLL cells has not been demonstrated. It is possible that complement deposition on Rituximab opsonised cells inhibits binding of the anti-Rituximab antibody to cell bound Rituximab (3).
Formulation PBS, pH 7.4
Label: FITC
State: Liquid purified IgG fraction from Tissue Culture Supernatant
Stabilizer: 1% BSA
Preservative: 0.09% Sodium Azide
Concentration 0.1 mg/ml
Purification Affinity Chromatography on Protein G
Conjugation FITC
Background Rituximab is a therapeutic reagent directed against the human CD20 cell surface antigen.
Synonyms Rituxan, MabThera
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